Description

2-Amino-6-Iodo-4-[(Trifluoromethyl)Sulphanyl]Phenol, 2-Hydroxy-3-Iodo-5-[(Trifluoromethyl)Thio]Aniline is a specialized halogenated aniline derivative that serves as a high-value pharmaceutical intermediate and organic synthesis building block. Its unique structure, featuring iodine and a trifluoromethylthio group, makes it a critical precursor for developing novel active compounds in medicinal chemistry. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the iodine and sulfur-containing functional groups.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Fluorinated Compound Library: An essential component for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Organic Electronic Materials: Potential monomer or dopant in the research of advanced organic semiconductors and conductive polymers.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	2-Amino-6-Iodo-4-[(Trifluoromethyl)Sulphanyl]Phenol, 2-Hydroxy-3-Iodo-5-[(Trifluoromethyl)Thio]Aniline
CAS No.	1448858-58-9
Molecular Formula	C7H5F3INOS
Molecular Weight	334.09 g/mol
Synonyms	2-Amino-6-iodo-4-[(trifluoromethyl)thio]phenol; 2-Hydroxy-3-iodo-5-[(trifluoromethyl)thio]aniline; 5-Amino-2-iodo-4-(trifluoromethylthio)phenol; 4-(Trifluoromethylthio)-6-iodobenzene-1,3-diol; 2-Iodo-4-(trifluoromethylthio)resorcinol; 3-Iodo-5-(trifluoromethylthio)aminophenol; 1448858-58-9; 2-Amino-6-iodo-4-(trifluoromethylsulfanyl)phenol
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-Iodo-4-[(Trifluoromethyl)Sulphanyl]Phenol adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and high purity for research and development applications. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.