Description

1-(4-Fluorophenyl)-4-Methyl-1H-Pyrazol-5-Amine is a high-purity fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile aromatic amine scaffold with a fluorine substituent, enabling precise molecular modifications for enhanced bioactivity and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in constructing advanced pesticide and herbicide molecules, where the fluorine atom improves metabolic stability and target binding.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials requiring fluorinated heterocyclic components.
• Chemical Biology & Proteomics: Employed as a tagging or linking agent in probe development for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	1-(4-Fluorophenyl)-4-Methyl-1H-Pyrazol-5-Amine
CAS No.	1448854-96-3
Molecular Formula	C10H10FN3
Molecular Weight	191.21 g/mol
Synonyms	4-Methyl-1-(4-fluorophenyl)-1H-pyrazol-5-amine; 5-Amino-4-methyl-1-(4-fluorophenyl)-1H-pyrazole; 1H-Pyrazol-5-amine, 1-(4-fluorophenyl)-4-methyl-; 4-Methyl-1-(4-fluorophenyl)-1H-pyrazol-5-ylamine; 1-(p-Fluorophenyl)-4-methyl-1H-pyrazol-5-amine
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-4-Methyl-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.