Description

3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a key building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for research and production in pharmaceutical development, agrochemicals, and materials science, enabling the efficient construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Essential boron-containing reagent for forming carbon-carbon bonds in complex molecule assembly.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Building block for creating specialized ligands and organometallic catalysts.
• Materials Science Research: Intermediate in the synthesis of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Item	Details
Product Name	3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
CAS No.	1448810-83-0
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	4-Cyano-2,6-dimethylphenylboronic acid pinacol ester; 2,6-Dimethyl-4-cyanophenylboronic acid pinacol ester; (4-Cyano-2,6-dimethylphenyl)boronic acid pinacol ester; 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; PINACOL (4-CYANO-2,6-DIMETHYLPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.