Description

4,4,4-Trifluorobutyraldehyde Hydrate is a high-value fluorinated building block essential for advanced organic synthesis. This compound is particularly valued for introducing the trifluoromethyl group and aldehyde functionality into target molecules, enabling the development of novel compounds with enhanced properties. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorine for improved metabolic stability, lipophilicity, and bioactivity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated motifs, particularly in CNS and antiviral drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and performance.
• Advanced Polymer Chemistry: Employed to create fluorinated monomers and polymers for specialty coatings, membranes, and high-performance materials.
• Organic Synthesis & Catalysis: A versatile reagent for nucleophilic addition reactions, reductive amination, and as a substrate in cross-coupling reactions.
• Fluorine Chemistry Research: Fundamental reagent in academic and industrial R&D for exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Item	Detail
Product Name	4,4,4-Trifluorobutyraldehyde Hydrate
CAS No.	1448773-75-8
Molecular Formula	C4H7F3O2 (Hydrate form)
Molecular Weight	144.09 g/mol (Anhydrous basis)
Synonyms	4,4,4-Trifluorobutanal Hydrate; 4,4,4-Trifluorobutyraldehyde Monohydrate; 4,4,4-Trifluorobutanal Monohydrate; 4,4,4-Trifluoro-1-butanal Hydrate; 3,3,3-Trifluoropropanecarboxaldehyde Hydrate; TFBA Hydrate; 1-Butanal, 4,4,4-trifluoro-, hydrate (1:1)
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluorobutyraldehyde Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and highly volatile, it is recommended to keep the container under an inert gas (e.g., nitrogen or argon) and ensure it is tightly sealed when not in use to prevent degradation and loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.