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5-Ethylthiophene-2-Boronic Acid Pinacol Ester CAS NO 1447710-10-2


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CAS No.:1447710-10-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Ethylthiophene-2-Boronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a protected boronic acid derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex heterocyclic scaffolds.

Application

  • Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing functionalized thiophene rings.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
  • Material Science: Serves as a monomer or precursor in the creation of conjugated polymers and organic semiconductors for OLEDs, OFETs, and solar cells.
  • Chemical Research: A versatile reagent in academic and industrial laboratories for methodology development and the synthesis of complex organic molecules.
  • Ligand & Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name 5-Ethylthiophene-2-Boronic Acid Pinacol Ester
CAS No. 1447710-10-2
Molecular Formula C12H19BO2S
Molecular Weight 238.16 g/mol
Synonyms 5-Ethyl-2-thienylboronic acid pinacol ester; 2-(5-Ethylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Ethylthiophen-2-yl)boronic acid pinacol ester; 5-Ethylthiophene-2-boronic acid neopentyl glycol ester (common alternative); Pinacol (5-ethyl-2-thienyl)boronate; CAS 1447710-10-2; Boronic acid, B-(5-ethyl-2-thienyl)-, 1,1-dimethylethyl ester (related)
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Quality Control

Our 5-Ethylthiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically >97% (by HPLC/NMR). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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