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(6-(4-Hydroxypiperidin-1-Yl)Pyridin-3-Yl)Boronic Acid CAS NO 1446509-85-8


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CAS No.:1446509-85-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(6-(4-Hydroxypiperidin-1-Yl)Pyridin-3-Yl)Boronic Acid is a high-purity boronic acid derivative and a sophisticated organic building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing new active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
  • Suzuki-Miyaura Cross-Coupling: Serves as a critical boron-containing partner in palladium-catalyzed cross-coupling reactions to form biaryl and heterobiaryl structures.
  • Chemical Biology Probe Development: Used in the creation of molecular probes and tools for studying biological pathways and target engagement.
  • Agrochemical Research: Employed in the discovery and synthesis of new, more effective crop protection agents.
  • Material Science Precursor: Acts as a monomer or linker in the development of advanced organic materials and polymers.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name (6-(4-Hydroxypiperidin-1-Yl)Pyridin-3-Yl)Boronic Acid
CAS No. 1446509-85-8
Molecular Formula C10H15BN2O3
Molecular Weight 222.06 g/mol
Synonyms 1-(5-Borono-3-pyridinyl)-4-piperidinol; 4-Piperidinol, 1-(5-borono-3-pyridinyl)-; 1-(5-Boronopyridin-3-yl)-4-hydroxypiperidine; (6-(4-Hydroxy-1-piperidinyl)-3-pyridinyl)boronic Acid; 3-Pyridineboronic acid, 6-(4-hydroxy-1-piperidinyl)-; B-[6-(4-Hydroxypiperidin-1-yl)pyridin-3-yl]boronic Acid
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Quality Control

Our (6-(4-Hydroxypiperidin-1-Yl)Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤1.0%
Heavy Metals ≤20 ppm
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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