Description

2-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in the pharmaceutical and agrochemical sectors. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments focused on developing new active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing thiazole heterocycles for therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides where the thiazole moiety imparts biological activity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic ester coupling partner to introduce the 2-ethylthiazole moiety into target molecules under mild, palladium-catalyzed conditions.
• Chemical Synthesis & Process Development: Employed in route scouting and scale-up processes for the efficient production of complex organic molecules.
• Academic & Contract Research: A vital reagent for methodological studies in organic chemistry and for custom synthesis projects in CRO (Contract Research Organization) settings.

Basic Information

Item	Details
Product Name	2-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole
CAS No.	1446478-67-6
Molecular Formula	C11H18BNO2S
Molecular Weight	239.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethylthiazole; 2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; 2-Ethylthiazole-5-boronic acid pinacol ester; (2-Ethylthiazol-5-yl)boronic acid pinacol ester; 2-Ethyl-5-(pinacolboranyl)thiazole; 5-(Pinacolatoboryl)-2-ethylthiazole
EINECS	Contact for details

Quality Control

Every batch of 2-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Thiazole undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Our quality assurance protocols include advanced chromatographic and spectroscopic methods to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for assay, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0% (Typical 97-99%)
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.