Description

Cyclopropanamine, 1-(Fluoromethyl)- is a specialized fluorinated cyclopropylamine building block with the CAS registry number 1446084-65-6. This compound is a high-value intermediate prized for its unique three-membered ring structure and fluorine substitution, which are critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential protease inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating the metabolically stable cyclopropyl and fluorine motifs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluoromethylcyclopropylamine moiety can enhance biological activity and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile building block for designing activity-based probes and molecular tools to study enzyme function and protein interactions.
• Material Science Research: Investigated as a monomer or precursor for developing novel fluorinated polymers with specific surface properties.
• Medicinal Chemistry Library Construction: Employed in high-throughput and parallel synthesis to generate diverse compound libraries for screening against biological targets.

Basic Information

Product Name	Cyclopropanamine, 1-(Fluoromethyl)-
CAS No.	1446084-65-6
Molecular Formula	C4H8FN
Molecular Weight	89.11 g/mol
Synonyms	1-(Fluoromethyl)cyclopropanamine; (1-(Fluoromethyl)cyclopropyl)amine; 1-(Fluoromethyl)cyclopropan-1-amine; 1-Amino-1-(fluoromethyl)cyclopropane; Cyclopropanamine, 1-(fluoromethyl)-; FC-C3-NH2 (common abbreviation)
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanamine, 1-(Fluoromethyl)- is produced and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically by GC or HPLC), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.