Description

4-Chloro-2-Methylphenyltrifluoromethanesulphonate97% is a high-purity, specialty organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block, enabling the introduction of the trifluoromethanesulfonate (triflate) group, a highly reactive and excellent leaving group in cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex molecules via palladium-catalyzed cross-coupling reactions like Suzuki, Stille, and Negishi couplings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the triflate group facilitates the introduction of aryl moieties.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers and organic electronic materials with specific optoelectronic properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis and Contract Manufacturing: An essential reagent for custom synthesis organizations (CSOs) and CDMOs serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-Methylphenyltrifluoromethanesulphonate97%
CAS No.	1446016-75-6
Molecular Formula	C9H6ClF3O3S
Molecular Weight	286.65 g/mol
Synonyms	4-Chloro-2-methylphenyl trifluoromethanesulfonate; 4-Chloro-o-tolyl triflate; 2-Methyl-4-chlorophenyl trifluoromethanesulfonate; (4-Chloro-2-methylphenyl) trifluoromethanesulfonate; Trifluoromethanesulfonic acid 4-chloro-2-methylphenyl ester; 4-Chloro-2-methylphenyl triflate; 1446016-75-6; 4-Chloro-2-methylphenyltriflate
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methylphenyltrifluoromethanesulphonate97% is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure the identity, purity (≥97%), and consistency meet the stringent requirements of our global B2B clients. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.