Description

2-Fluoro-3-Methylphenyltrifluoromethanesulphonate97% is a high-purity, specialty organofluorine building block with the CAS number 1446016-74-5. This compound is a critical reagent in advanced organic synthesis, valued for its role in introducing functional groups and constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: Acts as an effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for biaryl bond formation.
• Fluorination Chemistry: Utilized as a triflate ester in nucleophilic substitution reactions to introduce other functional groups.
• Chemical Research & Development: An essential reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	2-Fluoro-3-Methylphenyltrifluoromethanesulphonate97%
CAS No.	1446016-74-5
Molecular Formula	C9H6F4O3S
Molecular Weight	270.20 g/mol
Synonyms	2-Fluoro-3-methylphenyl trifluoromethanesulfonate; 2-Fluoro-m-tolyl triflate; 3-Methyl-2-fluorophenyl trifluoromethanesulfonate; 2-Fluoro-3-methyl-1-trifluoromethanesulfonyloxybenzene; (2-Fluoro-3-methylphenyl) triflate; Trifluoromethanesulfonic acid 2-fluoro-3-methylphenyl ester; 1446016-74-5
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methylphenyltrifluoromethanesulphonate97% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure the specified purity and identity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.