Description

3,4-Bis-Carboxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester (Wx610192) is a high-purity, protected pyrrolidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Research: Used to introduce constrained, functionalized pyrrolidine scaffolds into peptide backbones to enhance stability and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Agrochemical Synthesis: Utilized as an intermediate in the development of advanced herbicides and plant growth regulators with specific stereochemical requirements.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic chemistry and for creating custom compound libraries for high-throughput screening.

Basic Information

Product Name	3,4-Bis-Carboxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester (Wx610192)
CAS No.	1445950-99-1
Molecular Formula	C14H23NO6
Molecular Weight	301.34 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3,4-bis(carboxymethyl)pyrrolidine; tert-Butyl 3,4-bis(carboxymethyl)pyrrolidine-1-carboxylate; 3,4-Bis(methoxycarbonylmethyl)-1-Boc-pyrrolidine (common precursor); 1-Boc-3,4-bis(carboxymethyl)pyrrolidine; Pyrrolidine-1-carboxylic acid, 3,4-bis(carboxymethyl)-, 1,1-dimethylethyl ester; WX-610192; Wx610192
EINECS	Contact for details

Quality Control

Every batch of 3,4-Bis-Carboxymethyl-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under a strict quality management system. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.