Description

9-Oxo-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-2-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for palladium-catalyzed coupling reactions to create biaryl and heterobiaryl structures prevalent in modern medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific fused ring systems.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in creating molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Academic & Contract Research: A valuable tool for synthetic methodology development and exploration of new chemical space in university and CRO laboratories.

Basic Information

Product Name	9-Oxo-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-2-Boronic Acid Pinacol Ester
CAS No.	1445800-18-9
Molecular Formula	C₁₇H₂₁BO₃
Molecular Weight	284.16 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7,8,9-tetrahydro-5H-benzocyclohepten-9-one; 9-Oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-boronic acid pinacol ester; 2-(9-Oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzocycloheptenone boronic ester; Tetrahydrobenzocycloheptenone pinacol boronate
EINECS	Contact for details

Quality Control

Every batch of 9-Oxo-6,7,8,9-Tetrahydro-5H-Benzocycloheptene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot performance suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.