Description

6-Fluoro-1-Methyl-1,2,3-Benzotriazole is a high-value, fluorinated benzotriazole derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a fluorine substituent and a fused triazole ring, makes it an essential intermediate for developing novel pharmaceuticals, agrochemicals, and functional materials. This compound is particularly sought after by R&D chemists and process development teams in the pharmaceutical and specialty chemical industries for constructing complex molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its rigid, heterocyclic structure.
• Chemical Research: Employed in academic and industrial laboratories as a versatile reagent for heterocyclic chemistry, fluorination studies, and the synthesis of complex molecular architectures.
• Ligand and Catalyst Development: The benzotriazole moiety can act as a directing group or a ligand in transition metal-catalyzed reactions, useful in fine chemical manufacturing.

Basic Information

Product Name	6-Fluoro-1-Methyl-1,2,3-Benzotriazole
CAS No.	1445322-54-2
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	1-Methyl-6-fluorobenzotriazole; 6-Fluoro-1-methyl-1H-benzotriazole; 1H-Benzotriazole, 6-fluoro-1-methyl-; 6-Fluoro-1-methylbenzotriazole; 1445322-54-2; 6-Fluoro-1-methyl-1H-benzo[d][1,2,3]triazole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 6-Fluoro-1-Methyl-1,2,3-Benzotriazole is monitored through in-process controls and validated analytical methods to ensure batch-to-batch consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.