Description

Chloro(2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl )(2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II) is a highly specialized, air-stable palladium complex designed for demanding cross-coupling reactions. This compound matters because it combines a privileged BINAP-derived phosphine ligand with a biaryl amine system, offering superior catalytic activity and selectivity for challenging substrates. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for synthesizing complex organic molecules, including active pharmaceutical ingredients (APIs) and functional polymers. The CAS number for this product is 1445085-60-8.

Application

This palladium catalyst is engineered for high-performance applications in synthetic organic chemistry, particularly where traditional catalysts fail.

• C-N Cross-Coupling Reactions: Buchwald-Hartwig amination for the synthesis of aryl amines, a key step in many drug molecules.
• C-C Bond Formation: Suzuki-Miyaura and related cross-coupling reactions to construct biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate Synthesis: Production of complex, sterically hindered intermediates for Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Potential use in enantioselective transformations due to the chiral BINAP backbone.
• Materials Science Research: Catalyzing the polymerization or functionalization of organic semiconductors and advanced polymers.
• Process Chemistry Development: Scaling up key coupling steps from laboratory to pilot plant with high efficiency and reproducibility.

Basic Information

Item	Details
Product Name	Chloro(2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl )(2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II)
CAS No.	1445085-60-8
Molecular Formula	C58H44ClNPPd
Molecular Weight	936.70 g/mol
Synonyms	Pd(BINAP)(2-Aminobiphenyl)Cl; Palladium(II) Chloride (BINAP)(2'-Amino-1,1'-biphenyl-2-yl) Complex; (2'-Amino[1,1'-biphenyl]-2-yl)chloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium; BINAP-Pd-Amine Complex; Chloro(rac-BINAP)(2'-amino-1,1'-biphenyl-2-yl)palladium(II); Palladium Catalyst for Buchwald-Hartwig Amination; [PdCl(2-NH2-biphenyl)(BINAP)]
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and catalytic performance. Certificates of Analysis (COA) detailing assay, impurity profiles, and spectroscopic data are available upon request. We adhere to strict internal quality protocols suitable for R&D and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C for long-term stability. The product is light-sensitive and should be handled in a controlled environment to maintain its catalytic efficacy. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Pd Content (ICP-OES)	10.5 - 11.5 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.