Description

1-(2-Methoxyethyl)Cyclobutane-1-Carbaldehyde is a specialized aldehyde building block featuring a cyclobutane core and a methoxyethyl side chain. This compound is valued for its unique steric and electronic properties, making it a versatile intermediate in advanced organic synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting cyclobutane-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides, where the cyclobutane ring can confer specific biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for various organic transformations, including reductive amination, Grignard reactions, and heterocycle formation.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials where the aldehyde functionality allows for cross-linking or functional group introduction.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex aroma chemicals and flavoring agents with unique structural motifs.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in both academic laboratories and corporate R&D centers.

Basic Information

Product Name	1-(2-Methoxyethyl)Cyclobutane-1-Carbaldehyde
CAS No.	1443981-27-8
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	1-(2-Methoxyethyl)cyclobutane-1-carboxaldehyde; Cyclobutane-1-carbaldehyde, 1-(2-methoxyethyl)-; 1-(2-Methoxyethyl)-1-cyclobutanecarbaldehyde; 1-(2-Methoxyethyl)cyclobutanecarbaldehyde; 1-(2-Methoxyethyl)cyclobutylmethanal; 1-(2-Methoxyethyl)-1-formylcyclobutane; (1-(2-Methoxyethyl)cyclobutyl)methanal
EINECS	Contact for details

Quality Control

Our production of 1-(2-Methoxyethyl)Cyclobutane-1-Carbaldehyde adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.