Description

[1,5]Naphthyridine-3-Boronic Acid CAS NO 1443112-44-4 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and material science industries to synthesize novel, complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the [1,5]naphthyridine scaffold.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the palladium-catalyzed formation of biaryl and heterobiaryl structures.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science & OLED Development: Building block for organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Academic & Contract Research: Fundamental research tool in university and CRO (Contract Research Organization) laboratories for methodological development and discovery chemistry.

Basic Information

Item	Details
Product Name	[1,5]Naphthyridine-3-Boronic Acid
CAS No.	1443112-44-4
Molecular Formula	C8H7BN2O2
Molecular Weight	174.96 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,5-naphthyridine; 1,5-Naphthyridin-3-ylboronic acid; (1,5-Naphthyridin-3-yl)boronic acid; 1,5-Naphthyridine-3-boronic acid pinacol ester; 3-Borono-1,5-naphthyridine; [1,5]Naphthyridine-3-Boronic Acid; 1443112-44-4
EINECS	Contact for details

Quality Control

Our [1,5]Naphthyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.