Description

Benzoxazole-5-Boronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of active pharmaceutical ingredients (APIs), advanced organic electronic materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those containing benzoxazole scaffolds with potential biological activity.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Facilitates the incorporation of benzoxazole units into polymer backbones to modify thermal stability and optical properties.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.

Basic Information

Product Name	Benzoxazole-5-Boronic Acid
CAS No.	1443112-43-3
Molecular Formula	C7H6BNO3
Molecular Weight	162.94 g/mol
Synonyms	(5-Boronobenzoxazole); 5-Benzoxazoleboronic Acid; Benzoxazol-5-ylboronic Acid; 1,3-Benzoxazol-5-ylboronic Acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole (Pinacol ester precursor); B-(1,3-Benzoxazol-5-yl)boronic Acid; 5-Borono-1,3-benzoxazole; 1443112-43-3
EINECS	Contact for details

Quality Control

Our Benzoxazole-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals (ICP-MS)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.