Description

2-(2,2-Dimethyl-2,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1443110-16-4 is a high-value, advanced boronic ester building block used in modern organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through targeted coupling reactions.
• Materials Science & OLED Development: Enables the synthesis of conjugated organic molecules for electronic materials, including organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Academic & Industrial R&D: A versatile tool for methodology development and exploring new chemical space in synthetic chemistry laboratories.
• Custom Synthesis & Contract Manufacturing: Employed in the production of bespoke fine chemicals and complex target molecules for clients.

Basic Information

Product Name	2-(2,2-Dimethyl-2,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1443110-16-4
Molecular Formula	C14H23BO4
Molecular Weight	266.14 g/mol
Synonyms	2-(2,2-Dimethyl-2,5-dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,2-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydrofuran; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2-dimethyl-2,5-dihydrofuran; Pinacol (2,2-dimethyl-2,5-dihydrofuran-3-yl)boronate; Dihydrofuran-3-ylboronic acid pinacol ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced boronic ester adheres to strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is verified through analytical techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.