Description

1-{2-[(2-Chlorobenzyl)Thio]Ethyl}-5-Oxopyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidinone carboxylic acid core functionalized with a chlorobenzylthioethyl side chain. This compound matters for its critical role as a sophisticated building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop next-generation drug candidates targeting a range of neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel small-molecule drug candidates.
• Neurological Drug Synthesis: Used in the synthesis of potential therapeutics targeting CNS disorders, leveraging its specific heterocyclic structure.
• Protease Inhibitor Development: Serves as a precursor in the creation of compounds designed to inhibit specific enzymatic activity.
• Chemical Biology Research: Employed as a tool compound or a tagged ligand in biochemical assays and target identification studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for clinical trial materials.
• Library Synthesis for High-Throughput Screening: Utilized to create diverse chemical libraries for drug discovery programs.

Basic Information

Product Name	1-{2-[(2-Chlorobenzyl)Thio]Ethyl}-5-Oxopyrrolidine-3-Carboxylic Acid
CAS No.	1440535-35-2
Molecular Formula	C14H16ClNO3S
Molecular Weight	313.80 g/mol
Synonyms	5-Oxo-1-[2-[(2-chlorophenyl)methyl]sulfanyl]ethyl]pyrrolidine-3-carboxylic acid; 1-[2-[(2-Chlorobenzyl)thio]ethyl]-5-oxopyrrolidine-3-carboxylic acid; 1-(2-((2-Chlorobenzyl)thio)ethyl)-5-oxopyrrolidine-3-carboxylic acid; 3-Carboxy-1-(2-((2-chlorobenzyl)thio)ethyl)-2-pyrrolidinone; Pyrrolidine-3-carboxylic acid, 1-[2-[(2-chlorophenyl)methyl]thio]ethyl]-5-oxo-; (2-Chlorobenzylthio)ethyl pyrrolidinone carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-{2-[(2-Chlorobenzyl)Thio]Ethyl}-5-Oxopyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.