Description

4-Methylpyrazole-5-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly those containing pyrazole and biphenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific biological activity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes.
• Catalyst Ligand Precursor: Utilized in the preparation of specialized ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and CRO laboratories.

Basic Information

Product Name	4-Methylpyrazole-5-Boronic Acid Pinacol Ester
CAS No.	1440520-87-5
Molecular Formula	C₁₀H₁₇BN₂O₂
Molecular Weight	208.07 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1H-Pyrazole-5-boronic acid, 4-methyl-, pinacol ester; 4-Methyl-1H-pyrazol-5-ylboronic acid pinacol ester; 4-Methyl-1H-pyrazole-5-boronic acid pinacol ester; 4-Methylpyrazole-5-boronic acid pinacol ester; 4-Methyl-5-(pinacolboranyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 4-Methylpyrazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.