Description

1-(4-Fluorobenzyl)-1H-Imidazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct fluorinated benzyl-imidazole core structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in areas requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Protease Inhibitor Development: Potential building block for compounds targeting enzymes like kinases or other proteases due to the imidazole carboxylic acid moiety.
• Bioconjugation & Labeling: The carboxylic acid group allows for conjugation to other molecules, peptides, or labels for diagnostic or research purposes.
• Chemical Biology Probes: Utilized in the creation of chemical probes to study biological pathways and protein function.
• Agrochemical Research: May find application in the research and development of new agrochemicals requiring fluorinated heterocyclic structures.

Basic Information

Product Name	1-(4-Fluorobenzyl)-1H-Imidazole-5-Carboxylic Acid
CAS No.	1439902-43-8
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-1H-imidazole-5-carboxylic acid; 1H-Imidazole-5-carboxylic acid, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)-1H-imidazole-5-carboxylic acid; 4-Fluoro-benzyl-1H-imidazole-5-carboxylic acid; 1-(4-Fluorobenzyl)imidazole-5-carboxylic acid; 1-(p-Fluorobenzyl)imidazole-5-carboxylic acid; 1-(4-Fluorobenzyl)-5-imidazolecarboxylic acid; 1439902-43-8
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-1H-Imidazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.