Description

(1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutyl)Methanamine is a high-value, fluorinated organic building block featuring a cyclobutyl core and a primary amine functional group. This compound is critical for medicinal chemistry and advanced material science, where its unique structure enables the fine-tuning of molecular properties such as lipophilicity, metabolic stability, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for CNS (Central Nervous System) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its amine functionality and steric profile.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced resins with tailored thermal and chemical resistance.
• Chemical Biology Probe: Utilized in the development of molecular probes and biochemical tools for studying enzyme function and cellular pathways.

Basic Information

Product Name	(1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutyl)Methanamine
CAS No.	1439900-12-5
Molecular Formula	C13H16F3N
Molecular Weight	243.27 g/mol
Synonyms	1-[[3-(Trifluoromethyl)phenyl]methyl]cyclobutanemethanamine; (1-{[3-(Trifluoromethyl)benzyl]}cyclobutyl)methanamine; α-(3-(Trifluoromethyl)benzyl)cyclobutanemethylamine; 1-((3-(Trifluoromethyl)benzyl)cyclobutyl)methanamine; Cyclobutanemethanamine, 1-[[3-(trifluoromethyl)phenyl]methyl]-; FC-1439900-12-5
EINECS	Contact for details

Quality Control

Our (1-[3-(Trifluoromethyl)Phenyl]Methylcyclobutyl)Methanamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.