Description

2-(1-m-Tolylcyclobutyl)Acetic Acid is a specialized organic compound featuring a cyclobutane ring substituted with a tolyl and an acetic acid functional group. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators with unique modes of action.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or additive for the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-(1-m-Tolylcyclobutyl)Acetic Acid
CAS No.	1439899-07-6
Molecular Formula	C13H16O2
Molecular Weight	204.27 g/mol
Synonyms	2-(1-(3-Methylphenyl)cyclobutyl)acetic acid; 2-[1-(3-Methylphenyl)cyclobutyl]acetic Acid; m-Tolylcyclobutylacetic Acid; 1-(m-Tolyl)cyclobutane-1-acetic Acid; 1439899-07-6; 2-(1-(m-Tolyl)cyclobutyl)ethanoic Acid
EINECS	Contact for details

Quality Control

Our 2-(1-m-Tolylcyclobutyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development from research to commercial scale with quality standards tailored to your project phase, including compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.