Description

1-[(3-Fluorophenyl)Methyl]Cyclopropylmethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a cyclopropyl ring with a fluorinated benzyl moiety, which are valuable for modulating the physicochemical and biological properties of target molecules. Pharmaceutical research and development organizations, particularly those focused on medicinal chemistry and drug discovery, are the primary users seeking this high-value intermediate.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization, leveraging the fluorine atom for metabolic stability and the cyclopropyl group for conformational restriction.
• Agrochemical Synthesis: Employed in the development of advanced crop protection agents, where its fluorinated aromatic system can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	1-[(3-Fluorophenyl)Methyl]Cyclopropylmethanamine
CAS No.	1439896-90-8
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	1-[(3-Fluorobenzyl)]cyclopropanemethanamine; N-[(3-Fluorophenyl)methyl]cyclopropanemethanamine; 1-[(3-Fluorobenzyl)amino]cyclopropane; Cyclopropanemethanamine, N-[(3-fluorophenyl)methyl]-; (3-Fluorobenzyl)(cyclopropylmethyl)amine; 1-(3-Fluorobenzyl)cyclopropylmethanamine
EINECS	Contact for details

Quality Control

Our 1-[(3-Fluorophenyl)Methyl]Cyclopropylmethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.