Description

2-{3-Azabicyclo[3.1.0]Hexan-6-Yl}Acetic Acid is a high-value, synthetically derived bicyclic amino acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its unique constrained bicyclic scaffold is essential for modulating the pharmacokinetic and pharmacodynamic properties of novel drug candidates, particularly in central nervous system (CNS) and antiviral research. This compound is primarily utilized by pharmaceutical R&D departments, agrochemical innovators, and specialty chemical manufacturers seeking to develop next-generation therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates targeting neurological disorders, viral infections, and metabolic diseases.
• Protease Inhibitor Development: Used in the research and synthesis of inhibitors for various proteolytic enzymes, leveraging its rigid, three-dimensional structure.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides or pesticides with specific modes of action.
• Ligand & Catalyst Design: Employed in creating novel chiral ligands for asymmetric catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop activity-based probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-{3-Azabicyclo[3.1.0]Hexan-6-Yl}Acetic Acid
CAS No.	1438270-98-4
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	2-(3-Azabicyclo[3.1.0]hexan-6-yl)acetic acid; 3-Azabicyclo[3.1.0]hexane-6-acetic acid; 6-Carboxymethyl-3-azabicyclo[3.1.0]hexane; (3-Azabicyclo[3.1.0]hex-6-yl)acetic acid; Bicyclic amino acid derivative; AZBC-AA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-{3-Azabicyclo[3.1.0]Hexan-6-Yl}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.