Description

3-Chloro-4-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogen and sulfur-containing structure for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, due to its functional handle for polymerization.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of chemical probes used in proteomics and diagnostic assay development.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligand systems for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic ester functionalities.

Basic Information

Product Name	3-Chloro-4-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	1438262-39-5
Molecular Formula	C₁₃H₁₈BClO₂S
Molecular Weight	284.60 g/mol
Synonyms	[3-Chloro-4-(methylthio)phenyl]boronic acid pinacol ester; 3-Chloro-4-methylsulfanylbenzeneboronic acid pinacol ester; Pinacol [3-Chloro-4-(methylthio)phenyl]boronate; (3-Chloro-4-(methylthio)phenyl)boronic acid pinacol ester; Boronic acid, B-[3-chloro-4-(methylthio)phenyl]-, 1,1-dimethylethyl ester; 3-Chloro-4-(methylmercapto)benzeneboronic acid pinacol ester; CAS 1438262-39-5
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.