Description

2-Bromo-4-Fluoro-5-Methyl-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic ester building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its bromo and fluoro substituents offer valuable sites for further functionalization. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs).
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials due to its aromatic, halogenated core.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution in academic and industrial labs.
• Complex Molecule Synthesis: Used as a scaffold for constructing more complex polycyclic or heterocyclic structures in total synthesis projects.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-Methyl-Benzoic Acid Methyl Ester
CAS No.	1437780-13-6
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl 2-Bromo-4-Fluoro-5-Methylbenzoate; Benzoic acid, 2-bromo-4-fluoro-5-methyl-, methyl ester; 2-Bromo-4-fluoro-5-methylbenzoic acid methyl ester; Methyl 2-bromo-4-fluoro-5-methylbenzoate; 1437780-13-6; 2-Bromo-4-fluoro-5-methyl methyl benzoate
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-Methyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.