Description

2-(3,4-Dichloro-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients, including drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex halogenated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific halogenated phenyl structures.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	2-(3,4-Dichloro-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1437779-89-9
Molecular Formula	C12H14BCl2FO2
Molecular Weight	303.95 g/mol
Synonyms	3,4-Dichloro-5-fluorophenylboronic acid pinacol ester; (3,4-Dichloro-5-fluorophenyl)boronic acid pinacol ester; 2-(3,4-Dichloro-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,4-Dichloro-5-fluorobenzeneboronic acid pinacol ester; Pinacol (3,4-dichloro-5-fluorophenyl)boronate; 3,4-Dichloro-5-fluorophenyl-Bpin; 1437779-89-9
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichloro-5-Fluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.