Description

3-Hydroxynaphthalene-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing naphthalene-based structures.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with tailored properties.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Useful for synthesizing novel bidentate ligands for transition metal catalysis.
• Polymer and Material Science: Incorporated into specialty polymers to modify thermal, optical, or mechanical properties.

Basic Information

Product Name	3-Hydroxynaphthalene-2-Boronic Acid Pinacol Ester
CAS No.	1437769-83-9
Molecular Formula	C₁₆H₁₉BO₃
Molecular Weight	270.14 g/mol
Synonyms	2-(3-Hydroxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Hydroxy-2-naphthaleneboronic Acid Pinacol Ester; 3-Hydroxy-2-naphthylboronic Acid Pinacol Ester; 2-(3-Hydroxy-2-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 3-Hydroxy-2-naphthaleneboronate; 3-Hydroxynaphthalene-2-Boronic Acid Pinacol Ester CAS NO 1437769-83-9
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxynaphthalene-2-Boronic Acid Pinacol Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive coupling reactions and research applications. A detailed Certificate of Analysis (COA) with specifications for identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.