Description

2-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, multi-functional boronic ester derivative, primarily utilized as a key synthetic intermediate in advanced organic synthesis. Its core value proposition lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures in research and industrial settings. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists developing active ingredients, functional polymers, and novel electronic materials.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-couplings for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the phenol and boronate functionalities for structural diversity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex, boron-containing aromatic compounds.
• Ligand Synthesis: The phenolic and boronate groups make it a useful starting material for creating novel catalysts and chelating agents.

Basic Information

Product Name	2-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	1437769-82-8
Molecular Formula	C₁₃H₁₉BO₄
Molecular Weight	250.10 g/mol
Synonyms	2-Hydroxy-3-methoxyphenylboronic acid pinacol ester; 3-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2-Methoxy-6-(pinacolatoboryl)phenol; Phenol, 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-(3-Methoxy-2-hydroxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.