Description

Chloro{(1S,2S)-1,2-Diphenyl-1-[(3-(η6-Phenyl)Propyl)Amino]-2-(Methylsulfonylamido)}Ruthenium(II) RuCl[(S,S)Teth-Msdpen] is a highly specialized chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and transfer hydrogenation reactions, enabling the production of single-isomer chiral intermediates. It is critically needed by pharmaceutical R&D and fine chemical synthesis teams focused on developing new active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins in pharmaceutical intermediate synthesis.
• Transfer Hydrogenation Reactions: Utilizing hydrogen donors like isopropanol or formic acid for chiral amine and alcohol synthesis.
• Pharmaceutical API Development: Production of chiral building blocks for cardiovascular, central nervous system (CNS), and antiviral drug candidates.
• Fine Chemical and Agrochemical Synthesis: Manufacture of enantiomerically pure intermediates for advanced materials and crop protection agents.
• Academic and Industrial Research: A key reagent for methodology development in organic synthesis and catalysis studies.
• Process Chemistry Optimization: Scaling up enantioselective routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Chloro{(1S,2S)-1,2-Diphenyl-1-[(3-(η6-Phenyl)Propyl)Amino]-2-(Methylsulfonylamido)}Ruthenium(II) RuCl[(S,S)Teth-Msdpen]
CAS No.	1437326-26-5
Molecular Formula	C29H31ClN2O2RuS
Molecular Weight	610.15 g/mol
Synonyms	RuCl[(S,S)-Teth-Msdpen]; (S,S)-Teth-Msdpen Ru(II) Chloride; Ruthenium(II) Chloride (S,S)-Teth-Msdpen Complex; Chiral Ruthenium Diphosphine-Diamine Complex; Asymmetric Hydrogenation Catalyst Ru-Teth-Msdpen; [RuCl((S,S)-Teth-Msdpen)]; N-((1S,2S)-1,2-Diphenyl-2-((methylsulfonyl)amino)ethyl)-3-(η6-phenyl)propan-1-aminiumchloridoruthenium(II)
EINECS	Contact for details

Quality Control

Our Chloro{(1S,2S)-1,2-Diphenyl-1-[(3-(η6-Phenyl)Propyl)Amino]-2-(Methylsulfonylamido)}Ruthenium(II) RuCl[(S,S)Teth-Msdpen] is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and elemental analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use and stored in a cool, dry place.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.