Description

2-[3-(4-Fluorophenyl)Ureidomethylene]Malonic Acid Diethyl Ester is a specialized organic intermediate featuring a ureidomethylene malonate core functionalized with a fluorophenyl group. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex heterocyclic and pharmaceutical scaffolds. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators leveraging its fluorinated aromatic structure.
• Heterocyclic Chemistry: Serves as a critical starting material for constructing complex nitrogen-containing heterocycles like pyrimidines, pyridines, and their fused analogs.
• Chemical Biology Probes: Employed in the creation of fluorescent tags or activity-based probes for studying enzymatic processes.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and catalysis within university and CRO laboratories.

Basic Information

Product Name	2-[3-(4-Fluorophenyl)Ureidomethylene]Malonic Acid Diethyl Ester
CAS No.	1437323-24-4
Molecular Formula	C₁₅H₁₇FN₂O₅
Molecular Weight	324.31 g/mol
Synonyms	Diethyl 2-[[(4-fluorophenyl)carbamoyl]aminomethylene]malonate; 2-[[(4-fluorophenyl)carbamoyl]aminomethylene]malonic acid diethyl ester; (4-Fluorophenyl)ureidomethylene-malonic acid diethyl ester; Ureidomethylene malonate derivative; Fluorophenyl ureido malonate ester; CAS 1437323-24-4
EINECS	Contact for details

Quality Control

Our 2-[3-(4-Fluorophenyl)Ureidomethylene]Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development, ensuring reliability for your critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.