Description

6-(Bromomethyl)-1,3-Dihydro-1-Hydroxy-3,3-Dimethyl-2,1-Benzoxaborole is a specialized benzoxaborole derivative that serves as a versatile and critical synthetic intermediate. Its value lies in the reactive bromomethyl group, which enables efficient functionalization and coupling reactions, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients, particularly boron-containing drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel boron-based therapeutics, including protease inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides and herbicides that leverage boron's unique mode of action.
• Material Science Research: Serves as a precursor for creating functionalized polymers and organic electronic materials with tailored properties.
• Cross-Coupling Reactions: The bromomethyl moiety acts as an effective handle for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Utilized to synthesize novel bidentate and tridentate ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Enables the attachment of boron-containing motifs to biomolecules (peptides, sugars) for diagnostic and therapeutic applications.

Basic Information

Product Name	6-(Bromomethyl)-1,3-Dihydro-1-Hydroxy-3,3-Dimethyl-2,1-Benzoxaborole
CAS No.	1437051-65-4
Molecular Formula	C11H14BBrO2
Molecular Weight	269.94 g/mol
Synonyms	1-Hydroxy-3,3-dimethyl-6-(bromomethyl)-2,1-benzoxaborole; 6-(Bromomethyl)-1-hydroxy-3,3-dimethyl-1,3-dihydro-2,1-benzoxaborole; 1,3-Dihydro-1-hydroxy-3,3-dimethyl-6-(bromomethyl)-2,1-benzoxaborole; Benzoxaborole, 1,3-dihydro-1-hydroxy-3,3-dimethyl-6-(bromomethyl)-; 6-Bromomethyl-1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborole
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)-1,3-Dihydro-1-Hydroxy-3,3-Dimethyl-2,1-Benzoxaborole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.