Description

3-(Dimethylamino)-1-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Prop-2-En-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiazole-based enone structure. This compound is critical for enabling precise chemical synthesis in the development of novel active pharmaceutical ingredients (APIs). It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways due to its reactive enone moiety.
• Material Science Precursor: Acts as a precursor for synthesizing functionalized organic materials and ligands for catalysis.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs).
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes from laboratory scale to pilot plant production for commercial API manufacturing.

Basic Information

Product Name	3-(Dimethylamino)-1-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Prop-2-En-1-One
CAS No.	1432581-09-3
Molecular Formula	C10H14N2OS
Molecular Weight	210.30 g/mol
Synonyms	5-(3-(Dimethylamino)acryloyl)-2,4-dimethylthiazole; 2,4-Dimethyl-5-(3-(dimethylamino)acryloyl)thiazole; 3-(Dimethylamino)-1-(2,4-dimethylthiazol-5-yl)prop-2-en-1-one; (E)-3-(Dimethylamino)-1-(2,4-dimethylthiazol-5-yl)prop-2-en-1-one; 5-(3-Dimethylamino-acryloyl)-2,4-dimethyl-thiazole; DMAP-TZ Enone; Thiazole Acrylic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of 3-(Dimethylamino)-1-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Prop-2-En-1-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and we support audits for cGMP compliance where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.