Description

2-(4-Cyclobutoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for complex, multi-ring structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for studying biological processes.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-(4-Cyclobutoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	1432572-02-5
Molecular Formula	C₁₆H₂₃BO₃
Molecular Weight	274.17 g/mol
Synonyms	4-Cyclobutoxyphenylboronic acid pinacol ester; (4-Cyclobutoxyphenyl)boronic acid pinacol ester; 2-(4-Cyclobutoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Cyclobutoxybenzeneboronic acid pinacol ester; Pinacol (4-cyclobutoxyphenyl)boronate; B-(4-Cyclobutoxyphenyl)boronic acid pinacol ester; CAS 1432572-02-5
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Cyclobutoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured and tested under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, assay, and impurity profiles as determined by HPLC, NMR, and other relevant techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.