Description

[2-Fluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetic Acid CAS NO 1431546-20-1 is a high-value boronic ester derivative featuring a reactive acetic acid functional group. This compound serves as a versatile and critical building block in modern synthetic chemistry, enabling the construction of complex molecules through cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially fluorinated biaryl structures.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and OFETs, due to its conjugated boronic ester system.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Ligand and Catalyst Development: Serves as a precursor for creating novel bidentate ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Essential for CDMOs and fine chemical suppliers producing bespoke compounds for client projects.

Basic Information

Product Name	[2-Fluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetic Acid
CAS No.	1431546-20-1
Molecular Formula	C14H18BFO4
Molecular Weight	280.10 g/mol
Synonyms	2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetic acid; (2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenylacetic acid; 2-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid; Pinacol (2-fluoro-4-(carboxymethyl)phenyl)boronate; 1431546-20-1; Boronic acid, B-[2-fluoro-4-(carboxymethyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our [2-Fluoro-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.