Description

1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-N,n-Dimethylmethanamine is a high-value boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biaryl motifs for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials, where fluorine substitution tunes electronic properties.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D pipelines.

Basic Information

Product Name	1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-N,n-Dimethylmethanamine
CAS No.	1431470-48-2
Molecular Formula	C15H23BFNO2
Molecular Weight	279.16 g/mol
Synonyms	4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzylamine; (4-(Dimethylaminomethyl)-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-4-(dimethylaminomethyl)phenylboronic acid pinacol ester; 1-(4-Fluoro-3-(pinacolatoboryl)phenyl)-N,N-dimethylmethanamine; N,N-Dimethyl-1-[4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanamine; CAS 1431470-48-2
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-N,n-Dimethylmethanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.