Description

(2R,3S,4S)-2,3,4-Tris(Benzyloxy)-4-(4-((Benzyloxy)Methyl)-2,2-Dimethyl-1,3-Dioxolan-4-Yl)-1-(4-Methylpiperazin-1-Yl)Butan-1-One is a sophisticated chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents. It is primarily utilized by research institutions, custom synthesis firms, and pharmaceutical manufacturers engaged in process development and scale-up for new drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex APIs, especially those targeting infectious diseases or metabolic disorders.
• Process Chemistry & Scale-Up: Used in route scouting, optimization, and pilot-scale production for new chemical entities (NCEs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing molecular libraries in drug discovery programs.
• Custom Synthesis: A critical component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.
• Academic Research: Employed in university and institutional labs for studying stereoselective synthesis and carbohydrate chemistry.

Basic Information

Product Name	(2R,3S,4S)-2,3,4-Tris(Benzyloxy)-4-(4-((Benzyloxy)Methyl)-2,2-Dimethyl-1,3-Dioxolan-4-Yl)-1-(4-Methylpiperazin-1-Yl)Butan-1-One
CAS No.	1431329-06-4
Molecular Formula	C44H53NO8
Molecular Weight	723.90 g/mol
Synonyms	1-(4-Methyl-1-piperazinyl)-2,3,4-tris-O-(phenylmethyl)-4-[4-[(phenylmethoxy)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-1-butanone; (2R,3S,4S)-1-(4-Methylpiperazin-1-yl)-2,3,4-tris(benzyloxy)-4-[4-(benzyloxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]butan-1-one; Benzyl-protected piperazinyl butanone derivative; Chiral dioxolane-piperazine intermediate; Tris-O-benzyl derivative; CAS 1431329-06-4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC, NMR, and chiral purity analysis. Certificates of Analysis (COA) are available upon request, detailing identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.