Description

4-(2-Methoxyethyl)-1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. Its core value lies in its boronic ester functional group, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Used in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, a fundamental step in modern organic synthesis.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) agents for target identification and validation.
• Library Synthesis for Drug Discovery: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	4-(2-Methoxyethyl)-1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1430057-93-4
Molecular Formula	C13H23BN2O3
Molecular Weight	266.15 g/mol
Synonyms	1-Methyl-4-(2-methoxyethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-4-(2-methoxyethyl)pyrazole; 4-(2-Methoxyethyl)-1-methyl-1H-pyrazole-5-boronic acid pinacol ester; 1-Methyl-4-(2-methoxyethyl)pyrazole-5-boronic acid pinacol ester; CAS 1430057-93-4; Pyrazole boronic ester derivative
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyethyl)-1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.