Description

(S)-tert-Butyl 1-(Tetrahydrofuran-3-Yl)Hydrazinecarboxylate CAS NO 1429510-48-4 is a high-purity chiral building block and Boc-protected hydrazine derivative of significant value in advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the precise introduction of a tetrahydrofuran-substituted hydrazine moiety. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Peptidomimetics & PROTACs: Serves as a versatile building block for constructing peptidomimetic scaffolds and Proteolysis Targeting Chimeras (PROTACs) in drug discovery.
• Ligand & Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic routes to complex molecules.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring this specialized chemical entity.

Basic Information

Product Name	(S)-tert-Butyl 1-(Tetrahydrofuran-3-Yl)Hydrazinecarboxylate
CAS No.	1429510-48-4
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	tert-Butyl (S)-1-(oxolan-3-yl)hydrazine-1-carboxylate; (S)-1-Boc-1-(tetrahydrofuran-3-yl)hydrazine; (S)-N-Boc-N'-(tetrahydrofuran-3-yl)hydrazine; (S)-N-(tert-Butoxycarbonyl)-N'-(tetrahydrofuran-3-yl)hydrazine; Boc-NH-NH-THF-3-yl (S); (S)-3-(N-Boc-hydrazino)tetrahydrofuran; (S)-1-(Tetrahydrofuran-3-yl)-2-(tert-butoxycarbonyl)hydrazine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(Tetrahydrofuran-3-Yl)Hydrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.