Description

2-Pyridineacetic Acid, 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value boronic ester derivative of pyridine, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Building block for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & R&D Laboratories: A versatile reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring bespoke boronic acid derivatives.

Basic Information

Product Name	2-Pyridineacetic Acid, 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	1428761-14-1
Molecular Formula	C14H20BNO4
Molecular Weight	277.12 g/mol
Synonyms	Methyl 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic Acid Methyl Ester; Methyl 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate; 2-Pyridinecarboxylic Acid, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-, Methyl Ester; 5-BPin-Picolinate Methyl Ester; 5-(BPin)-Picolinic Acid Methyl Ester; Methyl 5-Boronopicolinate, Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Pyridineacetic Acid, 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.