Description

Benzo[D]Isoxazole-5-Boronic Acid CAS NO 1428582-37-9 is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing the benzoisoxazole scaffold.
• Agrochemical Synthesis: Used in the research and production of new-generation herbicides, fungicides, and insecticides.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new catalytic processes and constructing complex molecular architectures.
• Ligand Synthesis: Intermediate for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Benzo[D]Isoxazole-5-Boronic Acid
CAS No.	1428582-37-9
Molecular Formula	C7H6BNO3
Molecular Weight	162.94 g/mol
Synonyms	5-Borono-2,1-benzisoxazole; 2,1-Benzisoxazole-5-boronic acid; 1,2-Benzisoxazol-5-ylboronic acid; Benzo[d]isoxazol-5-ylboronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]isoxazole (Pinacol ester precursor); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Benzo[D]Isoxazole-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.