Description

1-Bromo-4-Ethoxy-2,3-Dimethylbenzene is a high-purity, synthetically valuable brominated aromatic ether compound. It serves as a versatile and critical advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers requiring a reliable, high-quality building block for coupling reactions, ligand synthesis, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the bromo and ethoxy functionalities enable further chemical modifications.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and substituents.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig) as an electrophilic partner to create complex biaryl and other structures.
• Ligand and Catalyst Development: Useful for constructing novel phosphine or nitrogen-based ligands for homogeneous catalysis.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of dyes, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	1-Bromo-4-Ethoxy-2,3-Dimethylbenzene
CAS No.	1428234-61-0
Molecular Formula	C10H13BrO
Molecular Weight	229.12 g/mol
Synonyms	4-Bromo-1-ethoxy-2,3-dimethylbenzene; 2,3-Dimethyl-4-bromophenetole; 1-Ethoxy-4-bromo-2,3-dimethylbenzene; 4-Bromo-2,3-dimethylphenetole; Benzene, 1-bromo-4-ethoxy-2,3-dimethyl-; 2,3-Dimethyl-1-bromo-4-ethoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Ethoxy-2,3-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.