Description

4-Chloro-2-Methylthio-1-(Trifluoromethyl)Benzene is a high-value, multi-functional aromatic building block distinguished by its unique trifluoromethyl and methylthio substituents. This compound is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other functional materials requiring tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex molecular architectures.
• Chemical Research & Development: Essential for academic and industrial labs exploring new chemical entities and reaction pathways in fluorine chemistry.

Basic Information

Product Name	4-Chloro-2-Methylthio-1-(Trifluoromethyl)Benzene
CAS No.	1428234-60-9
Molecular Formula	C8H6ClF3S
Molecular Weight	226.65 g/mol
Synonyms	1-Chloro-4-(methylthio)-2-(trifluoromethyl)benzene; 2-Methylthio-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-α,α,α-trifluoro-2-(methylthio)toluene; 2-(Methylthio)-4-chlorobenzotrifluoride; 4-Chloro-2-(methylthio)benzotrifluoride; 2-Chloro-5-(trifluoromethyl)phenyl methyl sulfide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Methylthio-1-(Trifluoromethyl)Benzene is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.