Description

2-Cyclopropyl-4-(Trifluoromethoxy)Aniline is a high-purity, specialized aromatic amine building block featuring a cyclopropyl and a trifluoromethoxy substituent. This compound is valued for its unique structural motifs, which are critical for modulating the physicochemical and biological properties of advanced molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and crop protection agent synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for advanced polymers and functional materials, where its aromatic amine group can be utilized in polymerization or as a site for further chemical modification.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis or as a structural component in organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological pathways and target engagement within cellular systems.

Basic Information

Item	Details
Product Name	2-Cyclopropyl-4-(Trifluoromethoxy)Aniline
CAS No.	1428234-58-5
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	2-Cyclopropyl-4-(trifluoromethoxy)benzenamine; 4-(Trifluoromethoxy)-2-cyclopropylaniline; 2-Cyclopropyl-4-trifluoromethoxyaniline; 1-Amino-2-cyclopropyl-4-(trifluoromethoxy)benzene; Benzenamine, 2-cyclopropyl-4-(trifluoromethoxy)-; 2-CPA-TFMA (abbrev.); [1428234-58-5]
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-4-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.