Description

3-Chloro-2,6-Difluorothioanisole is a high-value, multi-functional aromatic building block characterized by its unique combination of halogen and thioether substituents. This compound matters for its critical role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluorothioanisole core provides specific bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its electron-rich thioether and halogenated aromatic system.
• Custom Synthesis and Contract Manufacturing: A crucial building block for custom synthesis houses serving the life sciences and specialty chemicals sectors.

Basic Information

Product Name	3-Chloro-2,6-Difluorothioanisole
CAS No.	1428234-53-0
Molecular Formula	C7H5ClF2S
Molecular Weight	194.63 g/mol
Synonyms	1-Chloro-2,6-difluoro-3-(methylthio)benzene; 3-Chloro-2,6-difluorophenyl methyl sulfide; Methyl 3-chloro-2,6-difluorophenyl sulfide; 2,6-Difluoro-3-chlorothioanisole; 3-Chloro-2,6-difluorobenzenethiol, methyl ether; 3-Chloro-2,6-difluoro-1-(methylthio)benzene; (3-Chloro-2,6-difluorophenyl)(methyl)sulfane
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluorothioanisole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including GC, HPLC, and NMR. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.