Description

1,1-Cyclobutanedicarboxylic Acid, 1-Methyl Ester is a specialized organic building block featuring a cyclobutane ring with a diester substitution pattern. This compound is valued for its unique steric and electronic properties, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those requiring constrained, alicyclic frameworks.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent for the development of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis: A valuable building block for academic and industrial research in methodologies like ring-opening, cycloaddition, and esterification reactions.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1,1-Cyclobutanedicarboxylic Acid, 1-Methyl Ester
CAS No.	1427503-02-3
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	1-Methyl 1,1-cyclobutanedicarboxylate; Dimethyl 1,1-cyclobutanedicarboxylate (common isomer); Methyl 1,1-cyclobutanedicarboxylic acid ester; Cyclobutane-1,1-dicarboxylic acid monomethyl ester; 1-Carbomethoxycyclobutane-1-carboxylic acid; 1-Methoxycarbonylcyclobutane-1-carboxylic acid; 1,1-Cyclobutanedicarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1,1-Cyclobutanedicarboxylic Acid, 1-Methyl Ester is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.