Description

Ethyl 2-(2,6-Dimethylmorpholin-4-Yl)-5-Nitrobenzoate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in modern medicinal chemistry, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and agrochemical companies focused on developing new molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas requiring morpholine-based scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities and improve drug-like properties.
• API Synthesis: Serves as a building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Agrochemical Research: Potential application as an intermediate in the development of novel pesticides or herbicides, leveraging its nitro-aromatic and heterocyclic structure.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) offering custom synthesis services from gram to kilogram scale.

Basic Information

Product Name	Ethyl 2-(2,6-Dimethylmorpholin-4-Yl)-5-Nitrobenzoate
CAS No.	1427460-20-5
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	Ethyl 5-nitro-2-(2,6-dimethylmorpholin-4-yl)benzoate; 2,6-Dimethylmorpholine-4-carboxylic acid, 5-nitro-, ethyl ester; Benzoic acid, 2-(2,6-dimethyl-4-morpholinyl)-5-nitro-, ethyl ester; 1427460-20-5; Ethyl 2-(2,6-dimethylmorpholino)-5-nitrobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(2,6-Dimethylmorpholin-4-Yl)-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.