Description

3-Bromo-2-Chloro-6-Hydroxy-Benzaldehyde is a halogenated benzaldehyde derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen and aldehyde functionalities into their target compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where specific halogen and aldehyde groups are required for functionality.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes due to its reactive aldehyde group for conjugation.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-2-Chloro-6-Hydroxy-Benzaldehyde
CAS No.	1427373-68-9
Molecular Formula	C7H4BrClO2
Molecular Weight	235.46 g/mol
Synonyms	2-Chloro-3-bromo-6-hydroxybenzaldehyde; 6-Hydroxy-3-bromo-2-chlorobenzaldehyde; 3-Bromo-2-chloro-6-hydroxybenzenecarboxaldehyde; Benzaldehyde, 3-bromo-2-chloro-6-hydroxy-; 1427373-68-9
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-6-Hydroxy-Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and propensity for oxidation, it is recommended to handle the material under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.