Description

[1-(4-Fluoropentyl)Indol-3-Yl]-Naphthalen-1-Ylmethanone is a synthetic cannabinoid receptor agonist research chemical of significant interest in pharmacological and biochemical research. Its precise molecular structure allows for the study of cannabinoid receptor interactions and signaling pathways. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories investigating novel therapeutic targets and receptor mechanisms.

Application

• Pharmacological Research: Used as a reference standard and active compound in studies targeting the endocannabinoid system (CB1 and CB2 receptors).
• Biochemical Assay Development: Serves as a key ligand in the development and validation of high-throughput screening assays for receptor binding and functional activity.
• Metabolic Pathway Analysis: Employed in in-vitro studies to investigate the metabolic stability and biotransformation pathways of synthetic cannabinoids.
• Analytical Reference Standard: Essential for the calibration of analytical equipment (HPLC, GC-MS, LC-MS) in forensic, toxicology, and quality control laboratories.
• Structure-Activity Relationship (SAR) Studies: A critical tool for medicinal chemists exploring the impact of fluoropentyl and naphthoyl modifications on cannabinoid receptor affinity and selectivity.
• Neuroscience Research: Applied in preclinical models to study the neurological effects and potential therapeutic windows of cannabinoid analogs.

Basic Information

Product Name	[1-(4-Fluoropentyl)Indol-3-Yl]-Naphthalen-1-Ylmethanone
CAS No.	1427325-95-8
Molecular Formula	C24H22FNO
Molecular Weight	359.44 g/mol
Synonyms	1-(4-Fluoropentyl)-3-(1-naphthoyl)indole; 1-Naphthalenyl[1-(4-fluoropentyl)-1H-indol-3-yl]methanone; CBL-2201; 5F-APINACA N-(1-naphthoyl) isomer; 5F-AKB48 N-(1-naphthoyl) isomer; 5F-APINACA 1-naphthoyl isomer; [1-(5-Fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone (isomeric form).
EINECS	Contact for details

Quality Control

Our [1-(4-Fluoropentyl)Indol-3-Yl]-Naphthalen-1-Ylmethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and GC-MS/LC-MS for structural verification and impurity profiling, to ensure high consistency and reliability for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to beige crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97% (Area Percent)
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.